Pdr. Spraggs et al., A PROSPECTIVE RANDOMIZED TRIAL OF THE USE OF SODIUM-BICARBONATE AND HYDROGEN-PEROXIDE EAR DROPS TO CLEAR A BLOCKED TYMPANOSTOMY TUBE, International journal of pediatric otorhinolaryngology, 31(2-3), 1995, pp. 207-214
This randomised prospective trial compared the efficacy of sodium bica
rbonate and hydrogen peroxide ear drops in clearing a blocked tympanos
tomy tube. Tympanostomy tubes, 110 in number, obstructed with blood or
inspissated secretions were randomised into treatment and control gro
ups Details of the operative procedure were retrospectively collected
from the patients notes. The patients were reviewed after 2 weeks for
both clinical and tympanometric evidence of clearance of the tube and
evidence of complications of the drops. There was no significant thera
peutic advantage between the two drops (P > 0.9), but in both treatmen
t arms there was a significant therapeutic advantage over a period of
observation (P < 0.05 in both groups). Otorrhoea and pain on instillin
g the drops occurred with equal incidence in both treatment groups. As
obstruction of tympanostomy tubes is a common occurrence which often
prompts surgical reventilation, there is great potential for cost savi
ngs if conservative treatment can be used effectively The treatments f
or obstructed tympanostomy tubes are reviewed and methods of preventio
n of this common occurrence are discussed.