CHARACTERIZATION OF CYCLIC-AMP PHOSPHODIESTERASE ISOZYMES IN RAT PAROTID-GLAND

Authors
IMAI A NASHIDA T SHIMOMURA H
Citation
A. Imai et al., CHARACTERIZATION OF CYCLIC-AMP PHOSPHODIESTERASE ISOZYMES IN RAT PAROTID-GLAND, Archives of oral biology, 40(2), 1995, pp. 165-168
Citations number
18
Categorie Soggetti
Dentistry,Oral Surgery & Medicine
Journal title
Archives of oral biology → ACNP
ISSN journal
00039969
Volume
40
Issue
2
Year of publication
1995
Pages
165 - 168
Database
ISI
SICI code
0003-9969(1995)40:2<165:COCPII>2.0.ZU;2-U
Abstract
Cyclic AMP phosphodiesterase (PDE) isozymes were isolated and characte rized from the soluble fraction of rat parotid gland. Four main peaks containing PDE activity were obtained by Q-Sepharose Fast Flow column chromatography. The four peaks were identified as PDEs I-IV by kinetic properties, molecular-weight analysis and their responses to effecter s and inhibitors.