Nutritional requirements of extremely premature infants are greater th
an those of other premature and full-term neonates. Nutrition support
for these infants should be initiated early in the neonatal period com
bined with the use of parenteral nutrition and minimal enteral feeding
s. Intermittent gastric gavage is the preferred method to provide ente
ral feeding until sucking and swallowing mechanisms are mature. Fortif
ied preterm human milk is the first choice of feeding, and the best su
bstitute is premature infant formulas. Multivitamin supplementation ma
y be necessary, depending on the daily intake of infant formula. Iron
supplementation can be initiated as early as two weeks of age.