Cd. Varela et al., INTRAVENOUS SEDATION FOR THE CLOSED REDUCTION OF FRACTURES IN CHILDREN, Journal of bone and joint surgery. American volume, 77A(3), 1995, pp. 340-345
The safety and efficacy of intravenous sedation with both a narcotic a
nd a benzodiazepine were evaluated in 104 consecutive children who had
closed reduction of a fracture. Six patients had a subsequent additio
nal reduction with intravenous sedation, so the study involved a total
of 110 procedures. The average dose of meperidine was 1.47 milligrams
per kilogram of body weight, and the average dose of midazolam was 0.
11 milligram per kilogram of body weight. The interval between inducti
on of the sedation and performance of the procedure averaged ten minut
es, and the total duration of the procedure averaged thirty-nine minut
es. There were no episodes of apnea or cardiorespiratory complications
. Ninety-six (92 per cent) of the initial 104 reductions were successf
ul, Only four patients subsequently needed general anesthesia for a re
peat closed reduction. The physician's satisfaction with the method of
sedation was good or excellent for 103 (94 per cent) of the 110 proce
dures. Eighty-one (93 per cent) of eighty-seven patients who were able
to respond had no memory of the reduction. A telephone survey conduct
ed after the procedure revealed that eighty-four (98 per cent) of eigh
ty-six parents who responded were satisfied with the method of sedatio
n. Intravenous sedation with a narcotic and a benzodiazepine proved to
be a safe and effective method of anesthesia for the closed reduction
of fractures in children in our series. Careful monitoring of the pat
ient after sedation is imperative.