CICATRIZATION EFFECT OF JATROPHA-CURCAS ( ANGIOSPERMAE, EUFORBIACEAE)LATEX ON ALBINO MICE

The wound healing effects of Jathopha curcas latex upon surgical wound produced in Balb/c mice skin, were studied with a modification of the Hoowes-Sooy-Harvey method. The effects of topical treatment using sin gle 50 ul doses of latex at different dilutions (10% to 100%) was comp ared with a multiple dose treatment (four 25 ul/dose q12h, latex 5% to 100%). The single dose treatment with 10%, 50% or 100% latex and the multiple dose treatment with dilutions between 5% and 10%, have a heal ing effeet but only on males. The multiple dose treatment with 50% or pure undiluted latex produced caustic lesions to treated skin.