Eq. Haxhija et al., VAGAL RESPONSE TO FEEDING TUBE INSERTION IN PRETERM INFANTS - HAS THEKEY BEEN FOUND, Early human development, 41(1), 1995, pp. 15-25
We prospectively studied the vagal response to feeding tube insertion
in eight healthy preterm infants, on three occasions in each infant du
ring the first three weeks of life. Heart rate, oxygen saturation, res
piration and cerebral blood flow velocities were assessed before, duri
ng and immediately after insertion of an orogastric feeding tube. The
whole procedure was recorded on video. The duration and quality of tub
e insertion and the behaviour of the infant were evaluated from the re
cordings. Twenty-one measurements in eight infants were evaluated, The
heart-rate decrease observed immediately after tube insertion correla
ted significantly with the duration of tube insertion, the quicker the
manipulation, the greater the heart-rate decrease (P = 0.000). The ma
ximal decrease of oxygen saturation after tube insertion correlated wi
th the degree of heart rate deceleration (P = 0.009), Significant alte
rations of the flow velocities were observed only when the heart rate
fell below 80 beats/min. We speculate that such episodes of bradycardi
a can be avoided by carefully inserting the feeding tube over a period
of at least 15 s.