A 10-year-old male suffering from acute optic neuritis is reported wit
h multiple silent cerebral lesions, which remained visible only with f
luid-attenuated inversion recovery sequences at 3-week intervals. Conv
entional sequences with magnetic resonance imaging did not visualize t
he lesions, Fluid-attenuated inversion recovery sequences are highly s
ensitive for the detection of silent lesions in acute optic neuritis.