HEMOLYTIC-UREMIC SYNDROME WITH PARTICULAR INVOLVEMENT OF BASAL GANGLIA AND FAVORABLE OUTCOME

Two children with hemolytic uremic syndrome and extrapyramidal complic ations are presented. Neuroimaging studies demonstrated bilateral basa l ganglia (striatal) involvement with favorable recovery in both patie nts. The pathophysiology of the neurologic complications in hemolytic uremic syndrome are probably multifactorial. Our patients suggest a re versible process because both patients recovered clinically and radiog raphically. Neurologic complications do not always portend a poor prog nosis and, in general, involvement of the basal ganglia is associated with favorable outcome.