Ka. Konigsreuther et Jb. Jonas, OPTIC DISC MORPHOLOGY IN DIABETES-MELLITUS, Graefe's archive for clinical and experimental ophthalmology, 233(4), 1995, pp. 200-204
Background: Diabetes mellitus is a systemic disease affecting multiple
tissues throughout the body. This study was performed to evaluate int
ravitally the diabetic changes of the optic disc Methods: Color photog
raphs of 115 eyes with varying severity of diabetic retinopathy and of
29 normal eyes were morphometrically examined Results: We found that
the size and shape of the optic disc, the neuroretinal rim and the par
apapillary atrophy did not differ significantly between the diabetic e
yes and the normal eyes. These variables were independent of the degre
e of diabetic retinopathy. There was a tendency toward decreased visib
ility of the retinal nerve fiber layer and increased optic disc pallor
in the diabetic eyes Conclusion: The results indicate that the area a
nd form of the optic disc, the neuroretinal rim and parapapillary atro
phy are not altered by diabetes mellitus. This is important for the di
agnosis of glaucoma in diabetic patients, since glaucoma leads to a de
crease of rim area and an enlargement of parapapillary atrophy. The re
duced visibility of the retinal nerve fiber layer, the increased optic
disc pallor and the unchanged size of the neuroretinal rim and parapa
pillary atrophy suggest that diabetes mellitus may be associated with
nonglaucomatous optic nerve atrophy.