A scale is presented that operationalizes the concept of meaning as it
is constructed within the context of life-threatening illness. Develo
pment of the scale is based on a symbolic interactionist perspective.
The reliability and validity of the scale are examined using a sample
of 422 persons with a variety of types of cancer at specified points i
n the illness trajectory. The scale was found to have item-total corre
lations ranging from 0.50 to 0.73, all significant at P<0.01, and a Cr
onbach's alpha of 0.81. A factor analysis indicated the total scale ex
plained 57.3% of the variance. Evidence of the scale's validity was fo
und in its ability to differentiate persons who were newly diagnosed a
s having non-metastatic cancer from those individuals experiencing the
first recurrence of cancer and those with metastatic disease, as well
as individuals experiencing a first remission from those experiencing
a first recurrence or those with metastatic disease. In addition, usi
ng regression analysis meaning was found to be predicted by social sup
port and specific coping strategies, and to be predictive of personal
control, body image and psychological adjustment. A bi-directional rel
ationship was demonstrated between the construction of meaning (primar
ily a cognitive phenomenon) and emotional response, which is congruent
with the bi-directional relationship between cognition and emotion as
proposed in the theory of Lazarus and Folkman.