POLYMORPHISM OF THE PENTANUCLEOTIDE REPEAT D(AAAAT) WITHIN INTRON-1 OF THE HUMAN TUMOR-SUPPRESSOR GENE P53 (17P13.1)

Authors
HAHN M FISLAGE R PINGOUD A
Citation
M. Hahn et al., POLYMORPHISM OF THE PENTANUCLEOTIDE REPEAT D(AAAAT) WITHIN INTRON-1 OF THE HUMAN TUMOR-SUPPRESSOR GENE P53 (17P13.1), Human genetics, 95(4), 1995, pp. 471-472
Citations number
3
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
95
Issue
4
Year of publication
1995
Pages
471 - 472
Database
ISI
SICI code
0340-6717(1995)95:4<471:POTPRD>2.0.ZU;2-6
Abstract
DyeDeoxy terminator cycle sequencing of allele-specific polymerase cha in reaction products has shown that there is a highly polymorphic d(AA AAT) pentanucleotide repeat within the first intron of the human p53 g ene. This provides a genetic marker for tumor suppressor p53 gene alte rations.