The results of a retrospective analysis of cases of gastric stump canc
er are reported. Among 298 gastric carcinomas treated between 1. 1. 19
86 and 1. 3. 1994, we found 28 (9.5%) cases of gastric stump cancer. G
astric carcinoma showed a male preponderance, with a male:female ratio
of ca. 4:1. Two thirds of the patients were older than 70 years at th
e time of diagnosis. In 27 of 28 patients the original operation perfo
rmed was a Billroth II resection without Braun's enteroanastomosis. Th
e mean time lag before the development of gastric stump cancer was sig
nificantly shorter in the group of patients older than 45 years at the
time of first operation (n=16) than in patients 45 years or younger (
n=12, P=0.03). Endoscopy with biopsy and endosonography were highly re
liable diagnostic instruments. The capability of CT for recognizing ly
mphatic metastasis is poor (42.1% sensitivity). The main risk factors
for the development of gastric stump cancer, according to our data, ar
e male sex, Billroth II resection for first reconstruction, age over 4
5 years at first operation, and gastric ulcer as reason for the origin
al gastric resection. The cost benefit ratio and timing of endoscopic
screening of partially gastrectomized patients are discussed.