PERIOPERATIVE HORMONAL-THERAPY IN LOCALLY ADVANCED ADENOCARCINOMA OF THE PROSTATE

Perioperative hormonal therapy is a potential therapeutic strategy tha t combines the advantages of systemic therapy and local surgical contr ol of adenocarcinoma of the prostate. In most cases, the use of hormon al therapy causes a reduction in the size of the prostate, some potent ial reduction in the volume of the cancer, and varying success in down staging of the malignancy. No study has shown any benefit in either su rvival or reduction of recurrences.