Mh. Roos et al., NEW GENETIC AND PRACTICAL IMPLICATIONS OF SELECTION FOR ANTHELMINTIC RESISTANCE IN PARASITIC NEMATODES, Parasitology today, 11(4), 1995, pp. 148-150
Investigations into genetic mechanisms underlying anthelmintic resista
nce in parasitic nematodes have indicated that even at moderate levels
of resistance, reversion to the initial level of susceptibility may b
e impossible Alleles that confer the higher levels of susceptibility m
ay be lost from the population in the early stages of selection. There
fore close monitoring of early steps in the selection for resistance i
s needed, as discussed here by Marleen Roos, Marcel Kwa and Warwick Gr
ant