The painful stimuli produced by a new generation of electrohydraulic/e
lectromagnetic lithotripters are such that continuous infusion analges
ia rather than general or regional anesthesia is appropriate. We descr
ibe our experience with continuous alfentanil infusion supplemented wi
th intravenous bolus midazolam in caring for patients treated with an
unmodified Medstone STS 1050 lithotripter. Ninety consecutive treatmen
ts using this technique averaged 63 minutes, compared with 69 minutes
for 14 treatments done with general anesthesia and 88 minutes for 58 t
reatments done with epidural anesthesia. The stone burden, kilovoltage
, and number of shocks were similar for the three groups, as was the i
mmediate stone fragmentation rate. Only 2 of 90 patients received inad
equate analgesia with the intravenous technique and required the induc
tion of general anesthesia. Continuous-infusion analgesia appears suff
icient to blunt the stimulus provided by the unmodified spark-gap lith
otripters still in common use.