PHYSICOCHEMICAL INVESTIGATION OF THE DIASTEREOISOMERIC SALT PAIR FORMED BY ALPHA-PHENYL-ETHYL-AMINE AND R-1-PHENYLETHYL-SUCCINAMIC ACID

Authors
KOZMA D POSZAVACA L ACS M POKOL G FOGASSY E
Citation
D. Kozma et al., PHYSICOCHEMICAL INVESTIGATION OF THE DIASTEREOISOMERIC SALT PAIR FORMED BY ALPHA-PHENYL-ETHYL-AMINE AND R-1-PHENYLETHYL-SUCCINAMIC ACID, Journal of thermal analysis, 44(2), 1995, pp. 339-344
Citations number
14
Categorie Soggetti
Chemistry Analytical
Journal title
Journal of thermal analysis → ACNP
ISSN journal
03684466
Volume
44
Issue
2
Year of publication
1995
Pages
339 - 344
Database
ISI
SICI code
0368-4466(1995)44:2<339:PIOTDS>2.0.ZU;2-F
Abstract
The diastereoisomeric salt pair formed between alpha-phenyl-ethyl-amin e and R-1-phenylethyl-succinamic acid were investigated by physico-che mical methods. Melting and solubility phase diagrams were determined, the coincidence of the eutectic points of the two phase diagrams were demonstrated. The large difference in physico-chemical properties of t he salt pair explains the efficient enantiomer separation.