STUDIES ON THE ANTIINFLAMMATORY AND RELATED PHARMACOLOGICAL ACTIVITIES OF PSIDIUM-GUAJAVA - A PRELIMINARY-REPORT

The methanolic fraction of Psidium guajava fruit extract was found to possess significant inhibitory activity against carragenin, kaolin and turpentine-induced oedema formation. The fraction significantly inhib ited protein exudation. The proliferative form of inflammation was sig nificantly counteracted following cotton pallet-induced granuloma form ation in rats. Acetic acid-induced algesia (writhing) in mice was sign ificantly inhibited by the fraction. Significant antipyretic activity of the fraction was observed following yeast-induced pyrexia in rats. Potent antiarthritic activity was observed with the fraction against f ormaldehyde-induced chronic arthritis in rats.