P. Lafond et al., JUSTIFICATION OF ROUTINE ASCITES PUNCTURE IN CIRRHOTIC-PATIENTS ADMITTED TO THE EMERGENCY DEPARTMENT, La Presse medicale, 24(11), 1995, pp. 531-533
Objectives: Spontaneous bacterial peritonitis (SBP) is a frequent, ser
ious, recurrent complication, occuring in 10 to 30% of cirrhotic patie
nts hospitalized with ascites. The key to diagnosis of SBP is ascites
paracentesis and polymorphonuclear count in ascitic fluid. The purpose
of our study was to evaluate sensitivity and specificity of clinical
and biological criteria in diagnosis of 5 BP. Methods: We prospectivel
y reviewed 30 adult cirrhotic patients admitted in our emergency depar
tment with ascites. Ascites paracentesis was performed in each patient
, and SBP diagnosis was based on either positive bacteriological cultu
re or polymorphonuclear count above 250/mm(3) in ascitic fluid. Classi
cal criteria for SBP were recorded: blood pressure under 90 mm of Hg,
abdominal pain, temperature above 385 degrees or under 365 degrees, ja
undice, encephalopathy, increased serum bilirubin or creatinine, leuko
cyte blood count above 12 G/I. We evaluated sensitivity and specificit
y of those criteria in SBP, and compared their frequency in patients w
ith SBP or sterile ascitic fluid. Results: Thirty patients were includ
ed in our series, and in 14 of them a SBP was diagnosed. A significant
difference was observed between spontaneous bacterial peritonitis and
sterile ascitic fluid for abdominal pain and temperature abnormalitie
s, but specificity and sensitivity of these criteria were very low. Mo
reover, SBP was asymptomatic in 7%. Conclusion: Due to the high rate o
f mortality in patients with SBP we recommend diagnostic procedures fo
r this frequent complication as soon as patient is admitted in emergen
cy department. This diagnosis must be based on ascitic fluid paracente
sis, which has to be performed, in the emergency department, in every
cirrhotic patient admitted with ascites. Indeed, SBP is often asymptom
atic, and no clinical or bacteriological criteria can be considered as
completely reliable for the diagnosis of spontaneous bacterial perito
nitis.