ALDOSTERONE AND TESTOSTERONE PRODUCING ADRENAL ADENOMA IN CHILDHOOD

An 8-year-old boy presented with precocious puberty and hypertension, He had hypokalemia, increased serum aldosterone and testosterone level s and low plasma renin activity. An adrenal adenoma was found using im aging methods and was removed. Postoperatively aldosterone, testostero ne and blood pressure returned to normal. Renal ultrasonography findin gs were consistent with nephrocalcinosis, which might be explained by long lasting hypokalemic metabolic alkalosis and hypercalciuria. Preco cious pseudopuberty progressed into true puberty due to the maturation al effect of testosterone. Nephrocalcinosis was still present 8 years later and hypertension was recurring obviously as a consequence of inc reased peripheral resistance.