We attempted to characterize the current prescribing practices and adm
inistration patterns for intravenous intermittent morphine in trauma p
atients in a multicenter, open prospective, observational study. The s
ubjects were 141 patients admitted to the surgical intensive care unit
s (ICU) of five United States trauma centers within 12 hours of injury
who received intermittent intravenous morphine for pain relief. The s
tudy was conducted from April 15, 1992, to February 15, 1993. Data obt
ained during the first 32 hours of the ICU stay included morphine regi
men, doses administered, and time between doses. One hundred sixty-one
orders were prescribed by surgeons. The most frequently ordered dose
was 2-4 mg and the most frequently ordered interval was every hour as
necessary. There was no relationship between the severity of injury an
d the minimum dose ordered. During the 492 nursing shifts studied, 125
7 doses were administered. Of these, 44% were at or below the minimum
amount prescribed by the surgeons. Thirty-three percent of the patient
s received a dose at an interval of more than 3 hours. We concluded th
at small amounts of narcotic analgesics are given to severely injured
patients, and amount ordered is not affected by the severity of injury
.