THICK CUTANEOUS MELANOMA OF THE TRUNK AND EXTREMITIES - AN INSTITUTIONAL REVIEW

Citation
Je. Spellman et al., THICK CUTANEOUS MELANOMA OF THE TRUNK AND EXTREMITIES - AN INSTITUTIONAL REVIEW, Surgical oncology, 3(6), 1994, pp. 335-343
Citations number
NO
Categorie Soggetti
Oncology,Surgery
Journal title
ISSN journal
09607404
Volume
3
Issue
6
Year of publication
1994
Pages
335 - 343
Database
ISI
SICI code
0960-7404(1994)3:6<335:TCMOTT>2.0.ZU;2-Z
Abstract
The objective of this study was to review our experience with thick cu taneous melanoma of the trunk and extremities and to identify subgroup s of long-term survivors. Ninety-one patients admitted between the yea rs 1977 and 1987, with cutaneous melanoma of the trunk or extremities, Breslow thickness greater than or equal to 4.0 mm, or a Clark's level V lesion form the basis of this review. Node positive clinical stage II patients had a 5-year survival rate of 32%. Five-year survival for node positive clinical stage III patients was 0% (P < 0.0001). Node ne gative clinical stage II patients, and those found to be histologicall y node positive, had no survival difference, P = 0.88. Sixty per cent of node negative patients with an extremity primary survived 5 years, while patients with a node positive truncal primary had a survival of 14%, P = 0.005. in conclusion, most patients present with local-region al disease. Patients with node negative extremity lesions have the bes t chance for cure.