CORTICOSTEROID RECEPTOR ANTAGONISTS - A CURRENT PERSPECTIVE

Authors
SUTANTO W DEKLOET ER
Citation
W. Sutanto et Er. Dekloet, CORTICOSTEROID RECEPTOR ANTAGONISTS - A CURRENT PERSPECTIVE, Pharmacy world & science, 17(2), 1995, pp. 31-41
Citations number
143
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Pharmacy world & science → ACNP
ISSN journal
09281231
Volume
17
Issue
2
Year of publication
1995
Pages
31 - 41
Database
ISI
SICI code
0928-1231(1995)17:2<31:CRA-AC>2.0.ZU;2-L
Abstract
This review aims to highlight a selection of antagonists for the miner alocorticoid and glucocorticoid receptors. Concepts of these receptor systems are described, as is the mechanism of action of these steroids in the brain and periphery. Examples of commonly available and newly synthesized antimineralocorticoids and antiglucocorticoids are given, together with their pharmacological profiles and, when appropriate, cl inical and therapeutic applications.