PRIMARY LEPTOMENINGEAL AMELANOTIC MELANOB LASTOMA

Leptomeningeal melanoblastosis is an uncommon but devastating malignan cy. A case of primary leptomeningeal amelanotic melanoblastosis in a 6 4-year old male is reported. Clinical findings included headache, atax ia, psychopathological disorders and progressive paraparesis. CT-scans of the brain showed an internal hydrocephalus. The disease was diagno sed on the basis of cerebrospinal fluid cytology by light microscopy. It was finally confirmed by autopsy which showed a primary melanoblast oma of the meninges with only few pigmented cells and radiculomedullar y infiltration.