Z. Dienes et P. Vogel, SYNTHESIS OF YLOXY)METHYL-4-DEMETHOXY-6,7-DIDEOXY-DAUNOMYCINON, A NEWDNA INTERCALATOR RELATED TO ANTHRACYCLINES, Bioorganic & medicinal chemistry letters, 5(6), 1995, pp. 547-550
The hydrochloride of (-)-(8R)-8-acetyl-7,8,9,10-tetrahydro-6, ydroxy-1
1-[3'-aminopropyloxy)methyl]naphthacene-5, 12-dione was derived from t
hyl)-2,3,5,6-tetramethylidene-7-oxabicyclo[2.2.2] heptane and shown to
be a moderate intercalator of calf thymus DNA type XV.