CMI-206 - A POTENT DUAL PLATELET-ACTIVATING-FACTOR ANTAGONIST AND 5-LIPOXYGENASE INHIBITOR

Authors
HUSSOIN MS CAI X SCANNELL RT YAEGER D KILLIAN DB ECKMAN J HWANG SB LIBERTINEGARAHAN L QIAN CG YEH CG IP S
Citation
Ms. Hussoin et al., CMI-206 - A POTENT DUAL PLATELET-ACTIVATING-FACTOR ANTAGONIST AND 5-LIPOXYGENASE INHIBITOR, Bioorganic & medicinal chemistry letters, 5(6), 1995, pp. 643-648
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
6
Year of publication
1995
Pages
643 - 648
Database
ISI
SICI code
0960-894X(1995)5:6<643:C-APDP>2.0.ZU;2-E
Abstract
CMI-206, phenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, was synthe sized and was found to antagonize PAF receptor binding and inhibit 5-l ipoxygenase activity both in vitro and in vivo.