D. Trivier et al., INFLUENCE OF IRON DEPLETION ON GROWTH-KINETICS, SIDEROPHORE PRODUCTION, AND PROTEIN EXPRESSION OF STAPHYLOCOCCUS-AUREUS, FEMS microbiology letters, 127(3), 1995, pp. 195-199
Growth rates, siderophore secretion, and bacterial proteins of two cli
nical isolates of Staphylococcus aureus were studied over 72 h of grow
th in iron-supplemented and iron-restricted chemically defined media.
Under iron restriction the growth rates were decreased to different ex
tents depending on the strain. Production of siderophore was detected
in the mid-exponential and stationary phases of growth. The expression
of iron-regulated proteins of 81, 23, and 17 kDa was time-dependent,
associated with the same stage of growth, and might be involved in sid
erophore efficiency.