A total of 17 presumptive killer yeast strains were tested in vitro fo
r growth inhibitory and killing activity against a range of fungal pat
hogens of agronomic, environmental and clinical significance. Several
yeasts were identified which displayed significant activity against im
portant pathogenic fungi. For example, isolates of the opportunistic h
uman pathogen, Candida albicans, were generally very sensitive to Will
iopsis mrakii killer yeast activity, whilst killer strains of Saccharo
myces cerevisiae and Pichia anomala markedly inhibited the growth of c
ertain wood decay basidiomycetes and plant pathogenic fungi. Results i
ndicate that such yeasts, together with their killer toxins, may have
potential as novel antimycotic biocontrol agents.