Clinical and endoscopic manifestations of 18 gastric inflammatory fibr
oid polyps (IFP) in 16 patients who underwent endoscopic or surgical r
emoval were retrospectively analyzed. All of the lesions were located
within the pyloric antrum, and the sizes varied from 0.8 to 7.0 cm. On
endoscopy, six polyps which measured 1.0 cm or less uniformly seemed
to be sessile or intramural tumors, whereas four of the nine polyps be
tween 1.1 and 2.0 cm in size were additionally accompanied by a centra
l depression. The remaining three, which measured more than 2.0 cm, sh
owed characteristic polypoid growth with ulcerations. Three polyps mor
e than 1.0 cm in size occasionally prolapsed into the duodenal bulb, T
hree patients with these prolapsing polyps and two with polyps accompa
nied by ulcerations experienced abdominal pain, nausea, or severe anem
ia. Two polyps (11%) were precisely diagnosed as IFP by means of conve
ntional forceps biopsy, Histological examinations revealed that all of
the polyps proliferated within the submucosa. Therefore, this type of
polyp may be subject to endoscopic removal to enable a precise diagno
sis and treatment.