COORDINATION CHEMISTRY OF ZINC WITH PHARMACEUTICAL LIGANDS - THE ZINC-ASPIRIN COMPLEX

Authors
HARTMANN U VAHRENKAMP H
Citation
U. Hartmann et H. Vahrenkamp, COORDINATION CHEMISTRY OF ZINC WITH PHARMACEUTICAL LIGANDS - THE ZINC-ASPIRIN COMPLEX, Bulletin of the Polish Academy of Sciences. Chemistry, 42(2), 1994, pp. 161-167
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Polish Academy of Sciences. Chemistry → ACNP
ISSN journal
02397285
Volume
42
Issue
2
Year of publication
1994
Pages
161 - 167
Database
ISI
SICI code
0239-7285(1994)42:2<161:CCOZWP>2.0.ZU;2-F
Abstract
The reaction between the sodium salt of aspirin (acetyl salicylic acid ) and zinc salts results in the formation of the zinc aspirin complex which was crystallized as Zn(acetylsaliclylate)(2)(H2O)(2). Its crysta l structure determination has revealed a severely distorted tetrahedra l coordination of the zinc ion with two monodentate carboxylate groups and two water molecules as ligands.