MAGNETISM OF BIOLOGICALLY-ACTIVE COPPER(II) CARBOXYLATES - MONOMER-DIMER EQUILIBRIUM

Biologically active copper(II) complexes with steroides type ligands w ere synthesized and its physical properties as well as molecular struc ture were examined. Ligands belong to the group of steroides which exi bit the versatile biological activity. They used to be applied as anti rheuma, antiinflammatory medicins and in the curing of posttreatment s hocks. Variable temperature magnetic susceptibility measurements and E PR spectra powdered samples indicated the monomeric and dimeric forms of the complexes in the solid state. There were carried out calculatio ns for the steroidal series of Cu(II) carboxylates. This research show s that steric effects, arising from bulky and the spheric shape of the ir functional groups, belong to the major causes of presence of monome ric forms in synthesized dimeric Cu(II) carboxylates. The electronic a nd infra-red spectra are strickly correlated with the magnetic and EPR data.