THEORETICAL CONFORMATIONAL-ANALYSIS OF INSECT NEUROPEPTIDE PROCTOLIN AND ITS SELECTED ANALOGS

Authors
ANGIELSKI A LIWO JA KONOPINSKA D CIARKOWSKI J
Citation
A. Angielski et al., THEORETICAL CONFORMATIONAL-ANALYSIS OF INSECT NEUROPEPTIDE PROCTOLIN AND ITS SELECTED ANALOGS, Bulletin of the Polish Academy of Sciences. Chemistry, 42(2), 1994, pp. 277-283
Citations number
19
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Polish Academy of Sciences. Chemistry → ACNP
ISSN journal
02397285
Volume
42
Issue
2
Year of publication
1994
Pages
277 - 283
Database
ISI
SICI code
0239-7285(1994)42:2<277:TCOINP>2.0.ZU;2-B
Abstract
There are presented the results of the Monte Carlo screening of the co nformational energy space accessible to insect neuropeptide proctolin and its several bioactive analogues obtained by modifications of the p eptide chain in positions 1 or 2 of the parent compound. By combining the Monte Carlo screening with the cluster analysis, conformations whi ch are common for most analogues under study could be found and descri bed.