Mm. Adams et al., THE RELATIONSHIP OF INTERPREGNANCY INTERVAL TO INFANT BIRTH-WEIGHT AND LENGTH OF GESTATION AMONG LOW-RISK WOMEN, GEORGIA, Paediatric and perinatal epidemiology, 11, 1997, pp. 48-62
To examine the association between interpregnancy interval and low bir
thweight (< 2500 g), preterm delivery (< 37 weeks' gestation), and ina
dequate fetal growth, we studied a population-based sample of 23 388 w
hite and 4885 black women at low risk for adverse pregnancy outcomes w
ho delivered their first and second infants in Georgia from 1980 to 19
92. We used fetal death and livebirth certificates. The interpregnancy
interval was the time from delivery to the woman's next conception. F
or each pregnancy outcome, we stratified by race and used logistic reg
ression to assess the association between interpregnancy interval and
outcome, while controlling for confounders. Intervals < 6 months were
observed for 3.7% of white women and 7.0% of black women and intervals
greater than or equal to 48 months were seen for 16.8% of white women
and 24.8% of black women. Results from logistic regression showed tha
t, for both races, interpregnancy interval was associated with low bir
th-weight and preterm delivery. Nearly all of the increased risk occur
red in intervals < 6 months or greater than or equal to 48 months. The
magnitude of the increase in risk associated with these intervals ran
ged from modest to moderate and was similar for black and white women.
Because short interpregnancy intervals are rare and are weak risk fac
tors among low-risk women, efforts to lengthen interpregnancy interval
s are unlikely to reduce substantially their rates of adverse pregnanc
y outcomes.