SYNTHESIS AND CATALYTIC PROPERTIES OF MANGANESE COMPLEXES OF SUBSTITUTED TETRAPHENYLPORPHYRINS IN THE STEREOSELECTIVE HYDROXYLATION OF CHOLESTEROL

Manganese(III) complexes of 5-(p-aminophenyl)-10,15,20-triphenylporphy rin, -(2-carboxyvinyl)-5,10,15,20-tetraphenylporphyrin, and their deri vatives containing electron-donor and electron-acceptor substituents h ave been synthesized. Manganese(III) porphyrinates (PMn) are catalytic ally active in the stereoselective hydroxylation of cholesterol to for m 3 beta,5 alpha-cholestanediol. The influence of substitutents in the porphyrin ring on the ability of PMn to associate in solution, the hy droxylation rate constants, and the turnover number of the catalyst ar e discussed.