The basic principles of positron annihilation physics are briefly disc
ussed and the three most important experimental techniques used for bu
lk studies are described (i.e. positron lifetime, angular correlation,
Doppler broadening). Several examples of the use of the positron meth
ods are discussed for metals, ceramics and molecular materials, which
illustrate the sensitivity of the positron annihilation techniques to
vacancy type defects. For example it is shown how information can be o
btained about vacancy formation energies, vacancy migration and cluste
ring, vacancy-impurity interactions, densities of rare gasses in bubbl
es in metals, and about free volume in molecular materials.