ASYMPTOMATIC VISCERAL LEISHMANIASIS IN A CHILD WITH ACUTE LYMPHOBLASTIC-LEUKEMIA

Citation
R. Mehrotra et al., ASYMPTOMATIC VISCERAL LEISHMANIASIS IN A CHILD WITH ACUTE LYMPHOBLASTIC-LEUKEMIA, The Journal of infection, 30(2), 1995, pp. 157-159
Citations number
13
Categorie Soggetti
Infectious Diseases
Journal title
ISSN journal
01634453
Volume
30
Issue
2
Year of publication
1995
Pages
157 - 159
Database
ISI
SICI code
0163-4453(1995)30:2<157:AVLIAC>2.0.ZU;2-#
Abstract
Visceral leishmaniasis was detected in a patient with acute lymphoblas tic leukaemia in remission, during maintenance therapy. Absence of fev er, a normal haemogram, normal serum globulins, a negative serology an d testicular involvement were the hallmarks of the case. Treatment wit h sodium stibogluconate (20 mg/kg for 55 days) failed. Subsequent ther apy with pentamidine resulted in complete parasite clearance. Prolonge d therapy with pentavalent antimony compounds or a higher dose of seco nd line drugs such as pentamidine are recommended for complete clearan ce.