Functional neuroimaging has assumed an important role in the cognitive
and clinical neurosciences. Recently, substantial progress has been m
ade toward developing functional magnetic resonance imaging techniques
for the examination of cerebral hemodynamic changes that accompany br
ain function and toward earlier and better diagnosis of brain disease.
Dynamic susceptibility contrast (DSC) MRI offers unique information a
bout cerebral hemodynamics both at rest and in response to brain activ
ation. We review the clinical applications of DSC MRI and present our
experience with this modality in the evaluation of patients with neuro
psychiatric disorders. Our experience suggests that DSC MRI may afford
new insights into the diagnosis and treatment of cognitive disorders.
(C) 1996 Academic Press, Inc.