From June 1987 to January 1993, 53 fractures complicated by overlying
blisters were identified and prospectively followed. Data concerning t
he mechanism of injury, time course in the development of the fracture
blisters, clinical characteristics of the blister, fracture type and
management, and soft-tissue treatment and outcome were collected. Clin
ically, two types of blisters were identified: clear fluid filled and
blood filled. Methods used to treat the skin blister were: aspiration
of the blister, deroofing of the blister with subsequent application o
f Silvadene cream or coverage with a nonadherent dressing, and leaving
the blister intact and covered by a loose gauze or exposed to the air
. No significant difference was found in the outcome of the skin injur
y treated with the various modalities. Nineteen patients underwent ear
ly open reduction and internal fixation in the presence of intact frac
ture blisters. In 17 cases the incision healed within 3 days, sealing
off the deeper structures, and reepithelialization of the blister bed
then occurred at a later date. Two of the patients who had incisions p
ass through blood-filled blisters developed wound healing complication
s. Although there was no significant difference in the outcome of the
soft-tissue treatment techniques, our present practice is to leave all
fracture blisters intact. If the blisters rupture spontaneously, they
are deroofed and covered with a nonadherent dressing. Early surgery i
s contemplated in patients with intact blisters and without severe swe
lling.