The relationship between nuclear magnetic resonance relaxation time ob
tained with magnetic resonance imaging (MRI) and muscle fiber composit
ion of the lateral gastrocnemius was examined in 13 men. There was a p
ositive correlation (r = 0.80, P less than or equal to 0.001) between
longitudinal relaxation time and the relative percentage of slow-twitc
h muscle fibers (type I). There was no relationship between transverse
relaxation time and type I percentage (r = 0.17, P = 0.57). These res
ults suggest that MRI longitudinal relaxation time can be used for the
noninvasive estimation of muscle fiber composition in humans.