RAT PHENOL-PREFERRING SULFOTRANSFERASE GENES (STP AND STP2) - LOCALIZATION TO MOUSE CHROMOSOME-7 AND CHROMOSOME-17

Authors
KHAN AS TAYLOR BR FILIE JD RINGER DP KOZAK CA
Citation
As. Khan et al., RAT PHENOL-PREFERRING SULFOTRANSFERASE GENES (STP AND STP2) - LOCALIZATION TO MOUSE CHROMOSOME-7 AND CHROMOSOME-17, Genomics, 26(2), 1995, pp. 417-419
Citations number
19
Categorie Soggetti
Genetics & Heredity
Journal title
Genomics → ACNP
ISSN journal
08887543
Volume
26
Issue
2
Year of publication
1995
Pages
417 - 419
Database
ISI
SICI code
0888-7543(1995)26:2<417:RPSG(A>2.0.ZU;2-E
Abstract
The phenol-preferring sulfotransferases aryl sulfotransferase IV and N -hydroxyarylamine sulfotransferase catalyze sulfate conjugation of N-h ydroxy-2-acetylaminofluorene, a metabolite capable of causing hepatoca rcinogenesis in rats. We utilized published cDNA sequences of these su lfotransferases to type the progeny of two multilocus crosses and dete rmined that the genes, aryl sulfotransferase (Stp) and N-hydroxyarylam ine sulfotransferase (Stp2), map to positions on mouse chromosomes 7 a nd 17. (C) 1995 Academic Press, Inc.