S. Zhang et al., FIBEROPTIC SENSOR-BASED ON FLUORESCENT INDICATOR FOR MONITORING PHYSIOLOGICAL PH VALUES, Medical & biological engineering & computing, 33(2), 1995, pp. 152-156
A fibre-optical sensor has been developed based on the fluoresecent in
dicator 8-hydroxyl-1,3,6-pyrene trisulphonic acid trisodium salt (HOPS
A) for monitoring physiological pH values. Dowex-1 strongly basic anio
n exchange resin is used as the medium to immobilise the indicator on
the end of an optical fibre. Polyurethane is coated on the sensor as t
he permeable membrane for H+. The properties of HOPSA in solution, as
well as when immobilised on the sensor, are studied and found to have
the potential for monitoring physiological pH values.