Seasonality and affective disorders in the Southern Hemisphere were in
vestigated in populations living in latitudes (40 degrees S) equivalen
t to those of the studies conducted in the Northern Hemisphere. The au
thors describe a patient with bipolar II affective disorder who was li
ving in a low-latitude area (Sao Paulo, latitude: 23 degrees 39' S). T
he patient experienced five episodes of affective disorder that began
in the summer and were characterized by symptoms typical of an autumn-
winter depression. During the last two depressive episodes, the sympto
ms remitted after a 4-week course of evening light therapy. The case c
alls attention to the possibility that seasonality may influence the n
atural history of affective disorders even in lower latitude regions.