7 NEW DIDEMNINS FROM THE MARINE TUNICATE TRIDIDEMNUM-SOLIDUM

Authors
SAKAI F STROH JG SULLINS DW RIENHART KL
Citation
F. Sakai et al., 7 NEW DIDEMNINS FROM THE MARINE TUNICATE TRIDIDEMNUM-SOLIDUM, Journal of the American Chemical Society, 117(13), 1995, pp. 3734-3748
Citations number
55
Categorie Soggetti
Chemistry
Journal title
Journal of the American Chemical Society → ACNP
ISSN journal
00027863
Volume
117
Issue
13
Year of publication
1995
Pages
3734 - 3748
Database
ISI
SICI code
0002-7863(1995)117:13<3734:7NDFTM>2.0.ZU;2-R
Abstract
Seven new didemnins-didemnins M (1), N (2), X (3), and Y (4), nordidem nin N (5), epididemnin A(1) (6), and acyclodidemnin A (7)-were isolate d from an extract of the Caribbean tunicate Trididemnum solidum. The s tructures of these compounds were assigned, based on FABMS, high-field NMR data, and chemical degradation studies. Biological activities of these peptides are also described.