SYNTHESIS AND OXIDATIVE CLEAVAGE OF THE MAJOR EQUILIBRIUM PRODUCTS OFASCOMYCIN AND FK-506

Authors
BAUMANN K OBERHAUSER B GRASSBERGER MA HAIDL G SCHULZ G
Citation
K. Baumann et al., SYNTHESIS AND OXIDATIVE CLEAVAGE OF THE MAJOR EQUILIBRIUM PRODUCTS OFASCOMYCIN AND FK-506, Tetrahedron letters, 36(13), 1995, pp. 2231-2234
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
13
Year of publication
1995
Pages
2231 - 2234
Database
ISI
SICI code
0040-4039(1995)36:13<2231:SAOCOT>2.0.ZU;2-1
Abstract
Ascomycin and FK 506 are converted into the 9-ketal isomers in high yi elds by simple treatment with Lewis acids. The structure of the 9-keta l isomer was confirmed by oxidative cleavage.