STEREOCONTROLLED SYNTHESES OF POLYHYDROXY INDOLIZIDINES, INCLUDING 8A-EPI-CASTANOSPERMINE, 6,8A-DIEPI-CASTANOSPERMINE AND 1,6-DIEPI-CASTANOSPERMINE, STARTING FROM MALIC-ACID
Fj. Leeper et S. Howard, STEREOCONTROLLED SYNTHESES OF POLYHYDROXY INDOLIZIDINES, INCLUDING 8A-EPI-CASTANOSPERMINE, 6,8A-DIEPI-CASTANOSPERMINE AND 1,6-DIEPI-CASTANOSPERMINE, STARTING FROM MALIC-ACID, Tetrahedron letters, 36(13), 1995, pp. 2335-2338
Stereocontrolled total syntheses of one trihydroxy indolizidine 15 and
three tetrahydroxy indolizidines, 17, 21 and 23 - all diastereoisomer
s of castanospermine - are described which use malic acid as the only
chiral starting material.