DETECTION OF AMPHOTERICIN B-RESISTANT CANDIDA ISOLATES IN A BROTH-BASED SYSTEM

Authors
REX JH COOPER CR MERZ WG GALGIANI JN ANAISSIE EJ
Citation
Jh. Rex et al., DETECTION OF AMPHOTERICIN B-RESISTANT CANDIDA ISOLATES IN A BROTH-BASED SYSTEM, Antimicrobial agents and chemotherapy, 39(4), 1995, pp. 906-909
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
39
Issue
4
Year of publication
1995
Pages
906 - 909
Database
ISI
SICI code
0066-4804(1995)39:4<906:DOABCI>2.0.ZU;2-U
Abstract
Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolat es. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a ser ies of resistant isolates.