PNEUMOCOCCAL RESISTANCE IN SOUTHWEST VIRGINIA

Resistance patterns of Streptococcus pneumoniae in southwest Virginia were determined for 100 consecutive, hospital-based isolates, mostly f rom adults. Oxacillin disk screening identified all resistant isolates , Sixteen percent of the isolates were penicillin resistant (10% were highly resistant). E-strip testing revealed the following MICs (in mic rograms per milliliter, with percentages of isolates in parentheses): cefotaxime, less than or equal to 0.5 (92%); ceftriaxone, less than or equal to 0.5 (95%); ceftizoxime, less than or equal to 0.5 (85%); ery thromycin, less than or equal to 1 (87%); ofloxacin, less than or equa l to 2 (80%);vancomycin, less than or equal to 1 (98%).