COMPARATIVE IN-VITRO ACTIVITIES OF L-695,256, A NOVEL CARBAPENEM, AGAINST GRAM-POSITIVE BACTERIA

Authors
MALANOSKI G COLLINS L ELIOPOULOS CT MOELLERING RC ELIOPOULOS GM
Citation
G. Malanoski et al., COMPARATIVE IN-VITRO ACTIVITIES OF L-695,256, A NOVEL CARBAPENEM, AGAINST GRAM-POSITIVE BACTERIA, Antimicrobial agents and chemotherapy, 39(4), 1995, pp. 990-995
Citations number
22
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
39
Issue
4
Year of publication
1995
Pages
990 - 995
Database
ISI
SICI code
0066-4804(1995)39:4<990:CIAOLA>2.0.ZU;2-4
Abstract
The in vitro activity of a prototype 2-aryl carbapenem, L-695,256, aga inst gram-positive bacteria was examined. All streptococci and oxacill in-susceptible and -resistant staphylococci were inhibited at concentr ations of less than or equal to 0.125, less than or equal to 0.125, an d 4 mu g/ml, respectively. The activity of L-695,256 was superior to t hat of imipenem against other organisms intrinsically resistant to bet a-lactams.