CD30 POSITIVE (KI-1) LARGE-CELL LYMPHOMA PRESENTING WITH PERICARDIAL CONSTRICTION

It is very uncommon for the initial presentation of malignant lymphoma to be one of cardiac involvement and for such involvement to precipit ate cardiac dysfunction attributable to constriction. We describe a CD 30 positive (Ki-1) anaplastic large cell lymphoma, T-cell type, in a 2 9-year-old man whose presentation was a short history of profound hemo dynamic impairment and whose clinical course was rapidly fatal. This p atient's constrictive physiology was attributable to diffuse infiltrat ion of the pericardium and epicardium by the Ki-1 lymphoma. Our descri ption of this patient is noteworthy, given that the clinical and patho logic features of Ki-1 lymphomas are still being characterized.