Ad. Kelion et al., ANTIPHOSPHOLIPID SYNDROME IN A PATIENT WITH RAPIDLY PROGRESSIVE FIBROSING ALVEOLITIS, Postgraduate medical journal, 71(834), 1995, pp. 233-235
The antiphospholipid syndrome is a thrombotic disorder which can occur
in a primary form or more classically in systemic lupus erythematosus
. An association between cryptogenic fibrosing alveolitis and the anti
phospholipid syndrome has not previously been reported. We describe a
patient with severe cryptogenic fibrosing alveolitis who developed pul
monary embolism and myocardial infarction in the presence of antiphosp
holipid antibody. The case also illustrates that worsening respiratory
function may represent superimposition of one lung pathology on anoth
er, and may not simply be a deterioration of the pre-existing disease.