Background: With the recent resurgence of tuberculosis in the United S
tates, it is unclear whether existing prevention strategies can succes
sfully control and eliminate the disease. We determined the extent to
which opportunities for prevention were missed among patients with tub
erculosis. Methods: For all patients with active tuberculosis reported
to the Oregon Health Division, Portland, from July 1991 through June
1992, we determined previous history of tuberculosis therapy, previous
tuberculin skin test status, the presence of medical conditions for w
hich skin testing is recommended, and previous health care. We then de
termined whether they had undergone preventive procedures in accordanc
e with current recommendations of the Advisory Council for the Elimina
tion of Tuberculosis. Results: Of 153 patients with active tuberculosi
s, 90 (59%) had indications for-but had not previously undergone-recom
mended procedures. Ten patients (7%) did not complete therapy for prev
ious disease; two (1%) did not complete preventive therapy; 12 (8%) wi
th known previous positive tuberculin skin tests and an indication for
preventive therapy never received it; and 66 (43%) with known indicat
ions for screening never received a skin test. Indications for skin te
sting included exposure to active tuberculosis (44%), predisposing med
ical conditions (83%), previous residence in an institution (24%), and
birth in a country with a high prevalence of tuberculosis (29%). Conc
lusions: Based on their known effectiveness, a major reduction in tube
rculosis morbidity could occur if preventive measures were fully imple
mented. Appropriate skin testing is a prevention strategy of major imp
ortance. Priorities should include working to change provider practice
to better ensure that persons with indications routinely receive tube
rculin skin tests.